BDBM50629083 CHEMBL5435861

SMILES Cc1n[nH]c2ccc(O[C@H]3CCCc4cc(ccc34)C#N)cc12

InChI Key InChIKey=QEWUVYRFGKBJCM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50629083   

LigandPNGBDBM50629083(CHEMBL5435861)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of LRRK2 G2019S mutant (unknown origin) using LRRKtide as substrate pre-incubated for 15 min and measured after 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50629083(CHEMBL5435861)
Affinity DataIC50: 62nMAssay Description:Inhibition of human LRRK2 G2019S mutant phosphorylation at S1292 in human HEK293 cells incubated for 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM50629083(CHEMBL5435861)
Affinity DataIC50: 137nMAssay Description:Inhibition of phosphorylated human LRRK2 G2019S mutant at S935 in human HEK293 cells incubated for 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed