BDBM50629139 CHEMBL5404435

SMILES CCOc1ccn(-c2ccc(F)cc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnc3cc(sc23)-c2cn(C)cn2)c(F)c1

InChI Key InChIKey=HVCCYRAHPMMFKT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50629139   

TargetMacrophage-stimulating protein receptor(Human)
Wellmarkerbio Co.

Curated by ChEMBL
LigandPNGBDBM50629139(CHEMBL5404435)
Affinity DataIC50: 0.410nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant RON (979 to 1400(end) residues) expressed in Sf21 cells incubated for 20 mins followed by ATP a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Wellmarkerbio Co.

Curated by ChEMBL
LigandPNGBDBM50629139(CHEMBL5404435)
Affinity DataIC50: 4nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Wellmarkerbio Co.

Curated by ChEMBL
LigandPNGBDBM50629139(CHEMBL5404435)
Affinity DataIC50: 9nMAssay Description:Inhibition of RON (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed