BDBM50629383 CHEMBL5434549

SMILES C[C@H]1CCN1c1nc2c(CCC2(F)F)c(n1)N1CC[C@H](CC(O)=O)C1

InChI Key InChIKey=PZTBTCUOQGBJRE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50629383   

TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM50629383(CHEMBL5434549 | US20250145619, Example 36)
Affinity DataIC50: 13.6nMAssay Description:I. Experimental Procedures:1) The compounds were transferred to a 384 reaction plates (PE, 6007290) with Echo (Labcyte, 550);2) After centrifugation,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Youngene Therapeutics

US Patent
LigandPNGBDBM50629383(CHEMBL5434549 | US20250145619, Example 36)
Affinity DataIC50: 49nMAssay Description:Inhibition of N-terminal his tagged human recombinant KHK-C expressed in Escherichia coli incubated for 60 mins in presence of ATP by ADP Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed