BDBM50629424 CHEMBL5406767

SMILES CCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccc(O)cc1

InChI Key InChIKey=IUDPSGPAEIGLED-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50629424   

TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50629424(CHEMBL5406767)
Affinity DataEC50:  230nMAssay Description:Agonist activity at human TLR7 in HEK-Blue hTLR7 cells assessed as increase in inducible SEAP level incubated for overnight by QUANTI-Blue reagent ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50629424(CHEMBL5406767)
Affinity DataEC50:  275nMAssay Description:Agonist activity at TLR7 in human Ramos-blue cells assessed as increase in NFkappaB activation incubated for 72 hrs by quanti-blue/SEAP reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetToll-like receptor 8(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50629424(CHEMBL5406767)
Affinity DataEC50:  1.25E+5nMAssay Description:Agonist activity at human TLR8 in HEK-Blue hTLR8 cells assessed as increase in inducible SEAP level incubated for overnight by QUANTI-Blue reagent ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed