BDBM50629481 CHEMBL5416825

SMILES [H][C@@]12CN(CCN1CC1=C(CC(C)(C)C[C@@]1([H])OCCCOC2)c1ccc(Cl)cc1)c1ccc(C(=O)NS(=O)(=O)c2ccc(NCC3(O)CCOCC3)c(c2)[N+]([O-])=O)c(c1)N1CCCOc2nc3[nH]ccc3cc12

InChI Key InChIKey=MWSBFCZHCUBFEH-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50629481   

TargetApoptosis regulator Bcl-2(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50629481(CHEMBL5416825)
Affinity DataKi:  0.223nMAssay Description:Inhibition of human Bcl-2 expressed in Escherichia coli BL21(DE3) T1R cells preincubated under shaking condition for 1 min and measured after 3 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetBcl-2-like protein 1(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50629481(CHEMBL5416825)
Affinity DataKi:  8.30nMAssay Description:Inhibition of human Bcl-xL expressed in Escherichia coli BL21(DE3) T1R cells preincubated under shaking condition for 1 min and measured after 3 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed