BDBM50630220 CHEMBL5421268
SMILES CC(C)(NC(=O)Cc1csc(NC(=O)CSc2nc3nccnc3c(=O)n2CCc2ccccc2)n1)c1ccccc1
InChI Key InChIKey=WBXQHPRLMAYBJC-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50630220
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha(Human)
Leibniz-Fmp
Curated by ChEMBL
Leibniz-Fmp
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:Inhibition of PI3KC2alpha deltaN domain (unknown origin) preincubated for 5 mins followed by substrate addition and measured after 20 mins in the pre...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha(Human)
Leibniz-Fmp
Curated by ChEMBL
Leibniz-Fmp
Curated by ChEMBL
Affinity DataIC50: 109nMAssay Description:Inhibition of recombinant GST-tagged human PI3KC2alpha (142 to 1412 residues) expressed in baculovirus expression system using PI lipid kinase as sub...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Human)
Leibniz-Fmp
Curated by ChEMBL
Leibniz-Fmp
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3KC2beta (unknown origin) using PI lipid kinase as substrate in the presence of 10 uM ATP by Adapta universal kinase assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase C2 domain-containing subunit gamma(Human)
Leibniz-Fmp
Curated by ChEMBL
Leibniz-Fmp
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3KC2gamma (unknown origin) in the presence of 10 uM ATP by Adapta universal kinase assayMore data for this Ligand-Target Pair