BDBM50630440 CHEMBL5396961

SMILES C[C@]1(COC[C@@H]1O)N1CCC(CC1)c1cc2cc(NC(=O)C3CC33CC3)ncc2cc1Cl

InChI Key InChIKey=ZUOYPKKUCQORTM-UHFFFAOYSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50630440   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck

Curated by ChEMBL

LigandBDBM50630440(CHEMBL5396961)Copy SMILESCopy InChI

Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant N-terminal GST-fused LRRK2 G2109S mutant (970 to 2527 residues) (unknown origin) using LRRKtide peptide as substrate assess...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/20/2024
Entry Details
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TargetMAP/microtubule affinity-regulating kinase 3(Human)
Merck

Curated by ChEMBL

LigandBDBM50630440(CHEMBL5396961)Copy SMILESCopy InChI

Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human full length MARK3 expressed in insect cells using CHKtide as substrate preincubated with compound for 15 mins followe...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/20/2024
Entry Details
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TargetSodium channel protein type 5 subunit alpha(Human)
Merck

Curated by ChEMBL

LigandBDBM50630440(CHEMBL5396961)Copy SMILESCopy InChI

Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells by QPatch voltage clamp assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/20/2024
Entry Details
Copy BDB DOIPubMed
Copy reaction URL