BDBM50630768 CHEMBL5289875

SMILES FS(=O)(=O)Oc1ccc2CN(C3CCC(=O)NC3=O)C(=O)c2c1

InChI Key InChIKey=RXYXBYLQECASPH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50630768   

TargetProtein cereblon(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50630768(CHEMBL5289875)
Affinity DataIC50: 255nMAssay Description:Displacement of BODIPY-lenalidomide from human N-terminal NanoLuc-fused CRBN expressed in HEK293T cells incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProtein cereblon(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50630768(CHEMBL5289875)
Affinity DataIC50: 256nMAssay Description:Inhibition of CRBN (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed