BDBM50630845 CHEMBL5435819

SMILES COc1cc(Nc2c(cnc3cc(OCCON4CCN(C)CC4)c(OC)cc23)C#N)c(Cl)cc1Cl

InChI Key InChIKey=HFGUPJNHEPCEHX-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50630845   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50630845(CHEMBL5435819)
Affinity DataIC50: 1nMAssay Description:Inhibition of human BCR-ABL1 M351T mutant by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50630845(CHEMBL5435819)
Affinity DataIC50: 1nMAssay Description:Inhibition of human BCR-ABL1 H396P mutant by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50630845(CHEMBL5435819)
Affinity DataIC50: 1nMAssay Description:Inhibition of human BCR-ABL1 Q252H mutant by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50630845(CHEMBL5435819)
Affinity DataIC50: 1nMAssay Description:Inhibition of human BCR-ABL1 Y253F mutant by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50630845(CHEMBL5435819)
Affinity DataIC50: 1nMAssay Description:Inhibition of human wild type BCR-ABL1 by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50630845(CHEMBL5435819)
Affinity DataIC50: 2nMAssay Description:Inhibition of human wild type c-Src by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50630845(CHEMBL5435819)
Affinity DataIC50: 47nMAssay Description:Inhibition of human BCR-ABL1 T315I mutant by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed