BDBM50630847 CHEMBL5433868

SMILES CS(=O)(=O)Cc1ccc(cc1)-c1cc(C(N)=O)c2ncnc(N[C@H]3CCCNC3)c2n1

InChI Key InChIKey=LZZWUHWFQRAPOH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50630847   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50630847(CHEMBL5433868)
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal GST-tagged full-length human HPK1 expressed in baculovirus infected Sf21 cells using MBP as substrate preincubated for 15 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed