BDBM50631536 CHEMBL5404726

SMILES COc1cc(CN2CC(=O)Nc3c(cc(Cn4ccn(C)c4=N)cc3C2=O)-c2ccc(F)cc2C)cc(OC)c1

InChI Key InChIKey=LYDQZWAZFFPXAQ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50631536   

TargetWD repeat-containing protein 5(Human)
Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50631536(CHEMBL5404726)
Affinity DataKi:  0.100nMAssay Description:Inhibition of 6His-SUMO tagged human WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold (DE3) cells incubated for 1 hr by TR-FRET assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed