BDBM50631639 CHEMBL5433160

SMILES CSc1ccc(CNC(=O)[C@@H]2CCCN(C2)c2ncnc3nn(cc23)-c2ccc(cc2)C(F)(F)F)cc1

InChI Key InChIKey=DBSWYQCSXRNOMX-UHFFFAOYSA-N

Data  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50631639   

TargetNicotinamide phosphoribosyltransferase(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50631639(CHEMBL5433160)
Affinity DataKd:  36nMAssay Description:Displacement of FP-probe ZN-2-102 from C-terminal His6-tagged wild type human NAMPT rear channel assessed as dissociation constant by fluorescence po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50631639(CHEMBL5433160)
Affinity DataEC50:  65nMAssay Description:Positive allosteric modulation of C-terminal His6-tagged wild type human NAMPT using NAM and PRPP as substrates measured for 1 hr by NMNAT1-coupled e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed