BDBM50631894 CHEMBL5434229

SMILES COCCC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc(n2)C(F)(F)F)CC1

InChI Key InChIKey=UUBRCCCOMNXSPK-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50631894   

TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse?Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50631894(CHEMBL5434229)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor in HEK293 cell membranes measured after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
National Institute On Drug Abuse?Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50631894(CHEMBL5434229)
Affinity DataKi:  9.60nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor in HEK293 cell membranes by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
National Institute On Drug Abuse?Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50631894(CHEMBL5434229)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]-5-HT from 5HT2B receptor in HEK293 cell membranes by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse?Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50631894(CHEMBL5434229)
Affinity DataKi:  127nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 receptor in HEK293 cell membranes measured after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
National Institute On Drug Abuse?Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50631894(CHEMBL5434229)
Affinity DataKi:  2.52E+3nMAssay Description:Displacement of [3H]-spiperone from D4 receptor in HEK293 cell membranes by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
National Institute On Drug Abuse?Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50631894(CHEMBL5434229)
Affinity DataKi:  3.17E+3nMAssay Description:Displacement of [3H]-5-HT from 5HT2C receptor in HEK293 cell membranes by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
National Institute On Drug Abuse?Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50631894(CHEMBL5434229)
Affinity DataKi:  4.42E+3nMAssay Description:Displacement of [3H]-5-HT from 5HT2A receptor in HEK293 cell membranes by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
National Institute On Drug Abuse?Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50631894(CHEMBL5434229)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-SCH23390 from D1 receptor in HEK293 cell membranes by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed