BDBM50632100 CHEMBL5398804

SMILES COCCOc1ccn2c(cnc2c1)-c1cncc(NCc2ccc(nc2)N2CCCC2)c1

InChI Key InChIKey=ZRGLSSVOAKPURB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50632100   

TargetMast/stem cell growth factor receptor Kit(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50632100(CHEMBL5398804)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human KIT V654A mutant using polyGT and ATP as substrate preincubated for 20 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50632100(CHEMBL5398804)
Affinity DataIC50: 110nMAssay Description:Inhibition of KIT (delta 560 to 576 residues) deletion/V654A double mutant autophosphorylation at Y703 in human GIST-430/654 harboring KIT (delta560 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed