BDBM50632111 CHEMBL5404693

SMILES Cn1cc(cn1)-c1ccc(CNc2cc(ncn2)-c2cnc3cc(OCCCN4CCC(C)(F)CC4)ccn23)cc1

InChI Key InChIKey=XJCXFVLRKSIQDI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50632111   

TargetMast/stem cell growth factor receptor Kit(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50632111(CHEMBL5404693)
Affinity DataIC50: 73nMAssay Description:Inhibition of KIT (delta 560 to 576 residues) deletion/V654A double mutant autophosphorylation at Y703 in human GIST-430/654 harboring KIT (delta560 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed