BDBM50632112 CHEMBL5432164

SMILES CN1CCN(CCOc2ccn3c(cnc3c2)-c2cc(NCc3ccc(cc3)-c3coc(C)n3)ncn2)CCC1=O

InChI Key InChIKey=PQVSUVLFLVTQMW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50632112   

TargetMast/stem cell growth factor receptor Kit(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50632112(CHEMBL5432164)
Affinity DataIC50: 54nMAssay Description:Inhibition of KIT (delta 560 to 576 residues) deletion/V654A double mutant autophosphorylation at Y703 in human GIST-430/654 harboring KIT (delta560 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed