BDBM50632153 CHEMBL5428085

SMILES CC(=O)N1CCC(n2ncc3c(Nc4cc(C)[nH]n4)nc(NCc4ccc(Cl)c(C(=O)Nc5cc(F)ccc5F)c4)nc32)CC1

InChI Key InChIKey=IYHJCLOZCBCODN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50632153   

TargetSerine/threonine-protein kinase PLK4(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632153BDBM50632153(CHEMBL5428085)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of PLK4 (unknown origin) incubated for 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632153BDBM50632153(CHEMBL5428085)
Affinity DataIC50: 43nMAssay Description:Inhibition of TRKA (unknown origin) using TK peptide as substrate incubated for 30 mins in presence of ATP by HTRF analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed