BDBM50632514 CHEMBL5424617

SMILES C[C@H]1CC[C@@H](N)CN1c1ncnc2[nH]c(Cl)c(-c3cccc(c3)C#N)c12

InChI Key InChIKey=IWFMUUASEIUTAN-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50632514   

LigandPNGBDBM50632514(CHEMBL5424617)
Affinity DataKi:  97nMAssay Description:Inhibition of full length human recombinant HPK1 expressed in baculovirus-infected insect cells using 5-FAM-KRRALSSLRA-COOH peptide as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
LigandPNGBDBM50632514(CHEMBL5424617)
Affinity DataIC50: 110nMAssay Description:Inhibition of MAP4K3 (unknown origin) by by FRET based Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
LigandPNGBDBM50632514(CHEMBL5424617)
Affinity DataIC50: 9.43E+3nMAssay Description:Inhibition of HPK1 in human Jurkat cells assessed as reduction in SLP76 phosphorylation pretreated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed