BDBM50632667 CHEMBL5414348

SMILES c1ccc(cc1)C(CCNC2CCNCC2)c3ccccc3

InChI Key InChIKey=XSQZAMQEHSISJA-UHFFFAOYSA-N

Data  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50632667   

TargetSon of sevenless homolog 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50632667(CHEMBL5414348)
Affinity DataEC50:  9.55E+3nMAssay Description:Agonist activity at SOS1 in human HeLa cells assessed as activation of p-ERK1/2 incubated for 30 mins by immunoblot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSon of sevenless homolog 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50632667(CHEMBL5414348)
Affinity DataEC50:  1.04E+4nMAssay Description:Activation of human SOS1 mediated nucleotide exchange in presence of BODIPY-GDP by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)