BDBM50632984 CHEMBL5429444

SMILES [2H]C([2H])([2H])Oc3cccc(c2cc(F)c(NC(=O)C1=C(C(=O)NS(C)(=O)=O)CCC1)c(F)c2)c3

InChI Key InChIKey=URHRIFUMIBUHCE-FIBGUPNXSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50632984   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Ludwig Maximilian University of Munich

Curated by ChEMBL
LigandPNGBDBM50632984(CHEMBL5429444 | US20250066290, Example 1/1)
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant DHODH by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Ludwig Maximilian University of Munich

Curated by ChEMBL
LigandPNGBDBM50632984(CHEMBL5429444 | US20250066290, Example 1/1)
Affinity DataIC50: 100nMAssay Description:The in vitro inhibition of hDHODH was measured using an N-terminally truncated recombinant hDHODH enzyme as described in J. Med. Chem. 2006; 49:1239....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2025
Entry Details
US Patent