BDBM50633117 CHEMBL5428556

SMILES c1cc(c(cc1Cl)N2CCN(CC2)C(=O)C34CC5CC(C3)CC(C5)C4)N

InChI Key InChIKey=SNWNZTLWPJKTEO-UHFFFAOYSA-N

Data  2 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50633117   

TargetBile acid receptor(Human)
Chinese Academy of Medical Sciences&Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50633117(CHEMBL5428556)
Affinity DataEC50:  1.04E+3nMAssay Description:Agonist activity at GST-tagged FXR (unknown origin) assessed as increase in recruitment of co-activator SRC-2 by LanthaScreen TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBile acid receptor(Human)
Chinese Academy of Medical Sciences&Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50633117(CHEMBL5428556)
Affinity DataEC50:  1.05E+3nMAssay Description:Agonist activity at Gal4-fused FXR LBD (unknown origin) transfected in HEK293T cells co-transfected with Peak12-Gal4UAS-luciferase reporter assessed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)