BDBM50633342 CHEMBL5410158

SMILES COc1ccc(\C=C\C(=O)c2ccc3OC(C)(C)C=Cc3c2O)cc1OCCCN1CCOCC1

InChI Key InChIKey=QKJKOCQFEZTVJK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50633342   

TargetHypoxia-inducible factor 1-alpha inhibitor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50633342(CHEMBL5410158)
Affinity DataIC50: 3.31E+3nMAssay Description:Inhibition of HIF-1 alpha transcriptional activity in human U-251 cells incubated for 24 hrs under hypoxia condition by luciferse reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed