BDBM50633569 CHEMBL5421894

SMILES [H][C@@]1(CC[C@@]2([H])[C@]3([H])C[C@H](OS([O-])(=O)=O)[C@@]4([H])C[C@H](OS([O-])(=O)=O)[C@H](C[C@]4(C)[C@@]3([H])CC[C@]12C)OS([O-])(=O)=O)[C@H](C)C\C=C(/C)C(C)(C)C(C)C

InChI Key InChIKey=XXSWYTSITMIFFJ-UHFFFAOYSA-K

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50633569   

TargetTyrosine-protein kinase JAK3(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50633569(CHEMBL5421894)
Affinity DataIC50: 520nMAssay Description:Inhibition of N-terminal His-tagged human JAK3 (795 to 1124 residues) expressed in Sf21 cells incubated for 30 mins in presence of ATP by LANCE Ultra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50633569(CHEMBL5421894)
Affinity DataIC50: 530nMAssay Description:Inhibition of N-terminal GST-tagged human TYK2 (871to 1187 residues) expressed in Sf21 cells incubated for 30 mins in presence of ATP by LANCE Ultra ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50633569(CHEMBL5421894)
Affinity DataIC50: 840nMAssay Description:Inhibition of N-terminal GST-tagged human JAK1 (850 to 1154 residues) expressed in Sf21 cells incubated for 30 mins in presence of ATP by LANCE Ultra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50633569(CHEMBL5421894)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of N-terminal His-tagged human JAK2 (826 to 1132 residues) expressed in Sf21 cells incubated for 30 mins in presence of ATP by LANCE Ultra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed