BDBM50633723 CHEMBL5413389

SMILES CC(C)c1ccc(cc1)S(=O)(=O)Nc1cnc(N2CCC(=CC2)c2ccccc2C)c(c1)C(O)=O

InChI Key InChIKey=QBPSQOOZNDJASU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50633723   

TargetKRas/Son of Sevenless Homolog 1(Human)
University of Nottingham Ningbo China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50633723BDBM50633723(CHEMBL5413389)
Affinity DataIC50: 6.70E+4nMAssay Description:Inhibition of his tagged SOS1/GST-tagged KRAS G12C mutant (unknown origin) protein-protein interaction incubated for 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed