BDBM50633857 CHEMBL5435052

SMILES CN(C)C(=O)[C@@H](NC(=O)c1cc(ccc1-c1ccc(cc1)C(F)(F)F)C(=O)NS(C)(=O)=O)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=HYEVBMMMXMVSJS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50633857   

TargetMHC class I polypeptide-related sequence A(Homo sapiens)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50633857(CHEMBL5435052)
Affinity DataIC50: 700nMAssay Description:Inhibition of NKG2D (unknown origin)/MICA (unknown origin) protein-protein interaction by cell-based TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetNKG2-D type II integral membrane protein(Homo sapiens)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50633857(CHEMBL5435052)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of NKG2D (unknown origin)/ULBP6 (unknown origin) protein-protein interaction by cell-based TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed