BDBM50634061 CHEMBL5179819

SMILES CCc1ccc(NC(=O)Nc2c[nH]c3ccccc23)cc1

InChI Key InChIKey=UJZDIKVQFMCLBE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50634061   

TargetStimulator of interferon genes protein(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634061BDBM50634061(CHEMBL5179819)
Affinity DataIC50: 112nMAssay Description:Inhibition of STING in mouse RAW-Dual cells transfected with HT-DNA /2',3'-cGAMP by luciferase based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634061BDBM50634061(CHEMBL5179819)
Affinity DataIC50: 156nMAssay Description:Inhibition of STING in human THP1-Dual KI-hSTING-R232 cells assessed as cGAMP-induced IRF luciferase expression incubated for 2 hrs by QUANTI-Luc rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634061BDBM50634061(CHEMBL5179819)
Affinity DataIC50: 202nMAssay Description:Inhibition of mouse STING in mouse RAW cells assessed as secreted luciferase reporter of interferon stimulated gene (ISG) measured after 24 hrs incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634061BDBM50634061(CHEMBL5179819)
Affinity DataIC50: 232nMAssay Description:Inhibition of human STING in human THP-1 Dual cells assessed as secreted luciferase reporter of interferon stimulated gene (ISG) measured after 24 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634061BDBM50634061(CHEMBL5179819)
Affinity DataIC50: 364nMAssay Description:Inhibition of STING in human THP1-Dual cells transfected with HT-DNA /2',3'-cGAMP by luciferase based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed