BDBM50634302 CHEMBL5417773

SMILES [H][C@]12[#6]-[#6][C@]([H])([#6]-[#7](-[#6]1)-c1nc(-[#8]C([2H])([2H])C34[#6]-[#6]-[#6]-[#7]3-[#6]\[#6](-[#6]4)=[#6](\F)F)nc3c(F)c(ncc13)-c1cc(-[#8])cc3ccc(F)c(C#C)c13)[#7]2

InChI Key InChIKey=KQYJYAQKQXZHGA-FBCWWBABSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50634302   

TargetGTPase KRas(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50634302(CHEMBL5417773)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human GTP-bound KRAS wild type (1 to 169 residues) incubated for 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed