BDBM50634399 CHEMBL5401015

SMILES CC(=O)Nc1ccc2nc(NCc3ccc(O)c(c3)C(F)(F)F)sc2c1

InChI Key InChIKey=UUDVIKHRVVJUGZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50634399   

Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
University of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50634399(CHEMBL5401015)
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibition of recombinant 17beta-HSD10 (unknown origin) using E2 as substrate and NAD+ as cofactor preincubated for 5 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
University of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50634399(CHEMBL5401015)
Affinity DataIC50: 4.39E+3nMAssay Description:Inhibition of 17beta-HSD10 (unknown origin) expressed in HEK293 cells using (-)-CHANA probe as substrate assessed as decrease in fluorescence intensi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed