BDBM50634403 CHEMBL5433004

SMILES CC(=O)Nc1ccc2nc(NC(=O)Nc3ccc(O)c(Cl)c3)sc2c1

InChI Key InChIKey=JLNKZAOURVXTHS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50634403   

Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
University of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50634403(CHEMBL5433004)
Affinity DataKi:  250nMAssay Description:Inhibition of recombinant 17beta-HSD10 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as residual activity using acetoacetyl-CoA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
University of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50634403(CHEMBL5433004)
Affinity DataIC50: 340nMAssay Description:Inhibition of recombinant 17beta-HSD10 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as residual activity using acetoacetyl-CoA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
University of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50634403(CHEMBL5433004)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of recombinant 17beta-HSD10 (unknown origin) using E2 as substrate and NAD+ as cofactor preincubated for 5 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Sus scrofa)
University of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50634403(CHEMBL5433004)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of pig brain mitochondrial MAO-A using [3H]5-HT as substrate incubated for 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Sus scrofa)
University of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM50634403(CHEMBL5433004)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of pig brain mitochondrial MAO-B using [14C]PEA as substrate incubated for 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed