BDBM50635295 CHEMBL5505858

SMILES Nc1nc(=O)c2ncn([C@@H]3O[C@@H]4COP(=O)(O)O[C@H]5[C@@H](O)[C@H](n6cnc7c(N)ncnc76)O[C@@H]5COP(=O)(O)O[C@@H]3C4O)c2[nH]1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50635295   

TargetStimulator of interferon genes protein(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50635295(CHEMBL5505858)
Affinity DataKd:  70nMAssay Description:Binding affinity to recombinant human wild type STING expressed in Escherichia coli BL21 DE3 assessed as dissociation constant by Surface plasmon res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50635295(CHEMBL5505858)
Affinity DataEC50:  3.85E+4nMAssay Description:Agonist activity at human STING REF variant expressed in human THP-1 cells expressing IRF inducible SEAP reporter construct assessed as increase in i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50635295(CHEMBL5505858)
Affinity DataEC50:  5.35E+4nMAssay Description:Agonist activity at human STING HAQ variant expressed in human THP-1 cells expressing IRF inducible SEAP reporter construct assessed as increase in i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50635295(CHEMBL5505858)
Affinity DataEC50:  5.50E+4nMAssay Description:Agonist activity at human wild type STING expressed in human THP-1 cells assessed increase in IRF3 phosphorylation incubated for 6 hrs by Western blo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50635295(CHEMBL5505858)
Affinity DataEC50:  5.59E+4nMAssay Description:Agonist activity at human STING AQ variant expressed in human THP-1 cells expressing IRF inducible SEAP reporter construct assessed as increase in in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed