BDBM50635379 CHEMBL5556672

SMILES CCCCCCCCCCCCCC(=S)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1cccc(O)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50635379   

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Cornell University

Curated by ChEMBL
LigandPNGBDBM50635379(CHEMBL5556672)
Affinity DataIC50: 14nMAssay Description:Inhibition of human SIRT2 preincubated for 15 mins followed by H3K9Ac (KQTARK(Ac)STGGWW) peptide addition and measured after 5 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Cornell University

Curated by ChEMBL
LigandPNGBDBM50635379(CHEMBL5556672)
Affinity DataIC50: 30nMAssay Description:Inhibition of human Sirt2 deacetylation preincubated for 15 mins followed by H3K9-Ac substrate additionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Cornell University

Curated by ChEMBL
LigandPNGBDBM50635379(CHEMBL5556672)
Affinity DataIC50: 40nMAssay Description:Inhibition of human Sirt2 defatty-acylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Cornell University

Curated by ChEMBL
LigandPNGBDBM50635379(CHEMBL5556672)
Affinity DataIC50: 310nMAssay Description:Inhibition of human SIRT1 preincubated for 15 mins followed by H3K9Ac (KQTARK(Ac)STGGWW) peptide addition and measured after 5 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50635379(CHEMBL5556672)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human SIRT3 preincubated for 15 mins followed by H3K9Ac (KQTARK(Ac)STGGWW) peptide addition and measured after 10 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed