BDBM50635600 CHEMBL5555723

SMILES Cc1nn(C)cc1-c1oc2ncnc(Oc3ccc(NC(=O)c4cccn(-c5ccc(F)cc5)c4=O)cc3)c2c1-c1cccc(N)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50635600   

TargetTyrosine-protein kinase Mer(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50635600(CHEMBL5555723)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of MER (unknown origin) expressed in mouse BaF3 cells co-expressing TMEM assessed as inhibition of MER-driven cell proliferation incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50635600(CHEMBL5555723)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of AXL (unknown origin) preincubated for 15 mins followed by substrate and ATP addition and measured after 3 hrs by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase Mer(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50635600(CHEMBL5555723)
Affinity DataIC50: 45nMAssay Description:Inhibition of MER (unknown origin) preincubated for 15 mins followed by substrate and ATP addition and measured after 3 hrs by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed