BDBM50635634 CHEMBL5556274

SMILES CC(C)N1CCN(c2ccc(C(=O)n3nc(-c4ccccn4)nc3N)c3ccccc23)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50635634   

TargetCoagulation factor XII(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50635634(CHEMBL5556274)
Affinity DataIC50: 37nMAssay Description:Inhibition of FXIIa (unknown origin) using H-D-Pro-Phe-Arg-pNA as substrate incubated for 20 mins followed by substrate addition by spectrophotometri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProthrombin(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50635634(CHEMBL5556274)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of thrombin (unknown origin) using H-D-Phe-Pip-Arg-pNA-2HCl as substrate incubated for 20 mins followed by substrate addition by spectroph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetChymotrypsinogen B2(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50635634(CHEMBL5556274)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Chymotrypsin (unknown origin) using N-Suc-Ala-Ala-Pro-Phe-pNA as chromogenic substrate incubated for 20 mins followed by substrate addi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50635634(CHEMBL5556274)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of FXIa (unknown origin) using p-Glu-Pro-Arg-pNA.HCl as chromogenic substrate incubated for 20 mins followed by substrate addition by spec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCoagulation factor X(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50635634(CHEMBL5556274)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of FXa (unknown origin) using Z-D-Arg-Gly-Arg-pNA.2HCl as chromogenic substrate incubated for 20 mins followed by substrate addition by sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPlasminogen(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50635634(CHEMBL5556274)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of plasmin (unknown origin) using PyroGlu-Phe-Lys-pNA.HCl as chromogenic substrate incubated for 20 mins followed by substrate addition by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPlasma kallikrein(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50635634(CHEMBL5556274)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of PKal (unknown origin) using H-D-Pro-Phe-Arg-pNA-2HCl as substrate incubated for 20 mins followed by substrate addition by spectrophotom...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50635634(CHEMBL5556274)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of trypsin (unknown origin) using Bz-lle-Glu(gamma-OR)-Gly-Arg-pNA.HCl as chromogenic substrate incubated for 20 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTissue-type plasminogen activator(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50635634(CHEMBL5556274)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of tPA (unknown origin) using H-D-lle-Pro-Arg-pNA-2HCl as chromogenic substrate incubated for 20 mins followed by substrate addition by sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed