BDBM50635723 CHEMBL5532262

SMILES Cc1ncc(-c2cc(-c3ccc(S(=O)(=O)NCC(C)(C)O)cc3C)cnc2N)o1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50635723   

TargetPhosphatidylinositol 3-kinase regulatory subunit gamma(Homo sapiens)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50635723(CHEMBL5532262)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant PI3Kgamma using phosphatidylinositol as substrate in presence of [gamma33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Human)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50635723(CHEMBL5532262)
Affinity DataIC50: 300nMAssay Description:Inhibition of P13Kalpha (unknown origin) in the presence of ATP by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50635723(CHEMBL5532262)
Affinity DataIC50: 730nMAssay Description:Inhibition of P13Kdelta (unknown origin) in the presence of ATP by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Human)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50635723(CHEMBL5532262)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of P13Kbeta (unknown origin) in the presence of ATP by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed