BDBM50636009 CHEMBL5558965

SMILES COc1ccc(-c2c[nH]c3ncc(-c4ccc(N5CCNCC5)cc4)cc23)cc1OC

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50636009   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50636009(CHEMBL5558965)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-2(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50636009(CHEMBL5558965)
Affinity DataEC50:  90nMAssay Description:Activation of IL-2 in human Jurkat cells incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed