BDBM50636130 CHEMBL5556135

SMILES C=CC(=O)Nc1cccc(CN2C(=O)N(c3cc(OC)cc(OC)c3)Cc3cnc(Nc4c(C)cccc4NC(=O)C=C)nc32)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50636130   

TargetFibroblast growth factor receptor 4(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50636130(CHEMBL5556135)
Affinity DataIC50: 36nMAssay Description:Inhibition of human FGFR4 (445 to 753 residues) using preincubated for 30 mins followed by ATP plus poly (4:1 glu, tyr) addition and measured after 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 4(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50636130(CHEMBL5556135)
Affinity DataIC50: 107nMAssay Description:Inhibition of human FGFR4 C477A mutant using preincubated for 30 mins followed by ATP plus poly (4:1 glu, tyr) addition and measured after 30 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 4(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50636130(CHEMBL5556135)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human FGFR4 C552A mutant using preincubated for 30 mins followed by ATP plus poly (4:1 glu, tyr) addition and measured after 30 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 2(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50636130(CHEMBL5556135)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human FGFR2 (458 to 768 residues) using preincubated for 30 mins followed by ATP plus poly (4:1 glu, tyr) addition and measured after 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 3(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50636130(CHEMBL5556135)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human FGFR3 (450 to 758 residues) using preincubated for 30 mins followed by ATP plus poly (4:1 glu, tyr) addition and measured after 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50636130(CHEMBL5556135)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human FGFR1 (456 to 765 residues) using preincubated for 30 mins followed by ATP plus poly (4:1 glu, tyr) addition and measured after 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed