BDBM50636398 CHEMBL5532056
SMILES CC1=C(C(=O)OCC2CCCCC2)C(c2ccc(OC(F)F)c(OCC3CC3)c2)N(C(=O)SCc2ccccc2)C(=O)N1
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50636398
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C(Human)
Hainan University
Curated by ChEMBL
Hainan University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of PDE1C2 (147 to 531 residues) (unknown origin) using 3H-cGMP as substrate incubated for 15 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Hainan University
Curated by ChEMBL
Hainan University
Curated by ChEMBL
Affinity DataIC50: 597nMAssay Description:Inhibition of PDE10A (449 to 770 residues) (unknown origin) using 3H-cAMP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.68E+3nMAssay Description:Inhibition of PDE5A (535 to 860 residues) (unknown origin) using 3H-cGMP as substrateMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Human)
Hainan University
Curated by ChEMBL
Hainan University
Curated by ChEMBL
Affinity DataIC50: 1.76E+3nMAssay Description:Inhibition of PDE8A (480 to 820 residues) (unknown origin) using 3H-cAMP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.05E+3nMAssay Description:Inhibition of PDE4D (86 to 413 residues) (unknown origin) using 3H-cAMP as substrateMore data for this Ligand-Target Pair
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Hainan University
Curated by ChEMBL
Hainan University
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of PDE9A (181 to 506 residues) (unknown origin) using 3H-cGMP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 3.54E+3nMAssay Description:Inhibition of PDE2A (580 to 919 residues) (unknown origin) using 3H-cGMP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of PDE3A (679 to 1087 residues) (unknown origin) using 3H-cAMP as substrateMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Hainan University
Curated by ChEMBL
Hainan University
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of PDE7A (130 to 482 residues) (unknown origin) using 3H-cAMP as substrateMore data for this Ligand-Target Pair