BDBM50636647 CHEMBL5561544

SMILES CC(C)c1cc(-c2cc(C(=O)O)cn3cc(C(=O)N4CCCN(S(=O)(=O)c5ccccc5)CC4)nc23)ccc1C=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50636647   

TargetInterleukin-1 beta(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50636647(CHEMBL5561544)
Affinity DataIC50: 2.00E+5nMAssay Description:Antagonist activity at human recombinant His-tagged wild type IL-1 beta assessed as inhibition of IL-1 beta/Alexa 647 labeled human IL-1R1 (1 to 332)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 alpha(Homo sapiens)
Novartis

Curated by ChEMBL
LigandPNGBDBM50636647(CHEMBL5561544)
Affinity DataIC50: 2.00E+5nMAssay Description:Antagonist activity at human recombinant His-tagged wild type IL-1 alpha assessed as inhibition of IL-1 alpha/Alexa 647 labeled human IL-1R1 (1 to 33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed