BDBM506367 2-chloro-N-((1S,2R)-2-((S)-cyano(1-((1-(4- (cyclopropylsulfonyl)phenyl)azetidin-3-yl)methyl)piperidin-4- yl)(3-fluorophenyl)methyl)cyclopentyl)acetamide::US11045448, Cpd. No. 76

SMILES Fc1cccc(c1)[C@@](C#N)([C@H]1CCC[C@@H]1NC(=O)CCl)C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)C2CC2)CC1

InChI Key InChIKey=DXTZINIBCSTADU-PHDGFQFKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 506367   

TargetMenin(Homo sapiens (Human))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM506367(2-chloro-N-((1S,2R)-2-((S)-cyano(1-((1-(4- (cyclop...)
Affinity DataIC50:  5nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent