BDBM50636844 CHEMBL5542345

SMILES CNc1c2c(c([nH]n2)Cc3cccc(c3)Cl)nc(n1)Cl

InChI Key InChIKey=ULSNLRVQBCXMSH-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50636844   

TargetYTH domain-containing protein 1(Human)
University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636844BDBM50636844(CHEMBL5542345)
Affinity DataKd:  49nMAssay Description:Binding affinity to YTHDC1 (unknown origin) assessed as equilibrium dissociation constant by ITC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetYTH domain-containing protein 1(Human)
University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636844BDBM50636844(CHEMBL5542345)
Affinity DataIC50: 350nMAssay Description:Inhibition of GST-tagged YTHDC1 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetYTH domain-containing family protein 2(Human)
University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636844BDBM50636844(CHEMBL5542345)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of GST-tagged YTHDF2 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetYTH domain-containing family protein 3(Human)
University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636844BDBM50636844(CHEMBL5542345)
Affinity DataIC50: 8.30E+4nMAssay Description:Inhibition of GST-tagged YTHDF3 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetYTH domain-containing family protein 1(Human)
University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636844BDBM50636844(CHEMBL5542345)
Affinity DataIC50: 8.90E+4nMAssay Description:Inhibition of GST-tagged YTHDF1 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed