BDBM50637092 CHEMBL5557947::US12384772, Compound 1003

SMILES COc1ccc(S(=O)(=O)Nc2ccc(-c3cnc(N)s3)cc2)cc1OC

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50637092   

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50637092(CHEMBL5557947 | US12384772, Compound 1003)
Affinity DataKi:  200nMAssay Description:Binding affinity to sQC (unknown origin) assessed as inhibition constant at pH 6More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50637092(CHEMBL5557947 | US12384772, Compound 1003)
Affinity DataKi:  200nMAssay Description:10 mM compound stock solutions were prepared in DMSO. For IC50 determination compound stocks were serially diluted (1:3) in DMSO.All measurements wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase-like protein(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50637092(CHEMBL5557947 | US12384772, Compound 1003)
Affinity DataKi:  340nMAssay Description:Binding affinity to gQC (unknown origin) assessed as inhibition constant at pH 8More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50637092(CHEMBL5557947 | US12384772, Compound 1003)
Affinity DataKi:  340nMAssay Description:10 mM compound stock solutions were prepared in DMSO. For IC50 determination compound stocks were serially diluted (1:3) in DMSO.All measurements wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent