BDBM50637134 CHEMBL5518102

SMILES C=CC(=O)N1CCC[C@@H](n2nc(-c3ccc(Oc4ccn(C)c(=O)c4)c(C)c3)c3c(N)ncnc32)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50637134   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50637134(CHEMBL5518102)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of wild-type HER2 phosphorylation in human BT-474 cells incubated for 1 hr by In-cell Western assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50637134(CHEMBL5518102)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of wild-type human EGFR phosphorylation expressed in mouse NIH3T3 cells incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed