BDBM50637662 CHEMBL5542164
SMILES FC(F)(F)Oc1cccc(-c2cnc3ccc(-c4ccncc4)nn23)c1
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50637662
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
University of Sussex
Curated by ChEMBL
University of Sussex
Curated by ChEMBL
Affinity DataKd: 0.0100nMAssay Description:Binding affinity to biotinylated N-terminal TEV-fused/hexahistidine tagged C-terminal avidin tagged human DYRK1A kinase domain (127 to 485 residues) ...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
University of Sussex
Curated by ChEMBL
University of Sussex
Curated by ChEMBL
Affinity DataKd: 23nMAssay Description:Binding affinity to biotinylated N-terminal TEV-fused/hexahistidine tagged C-terminal avidin tagged human DYRK1A kinase domain (127 to 485 residues) ...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
University of Sussex
Curated by ChEMBL
University of Sussex
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Displacement of kinase tracer 236 from ATP-binding site of biotinylated N-terminal TEV-fused/hexahistidine tagged C-terminal avidin tagged human DYRK...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
University of Sussex
Curated by ChEMBL
University of Sussex
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Displacement of fluorescent tracer from ATP-binding site of N-terminal NanoLuc fused DYRK1A in HEK293 cells incubated for 2 hrs in presence of 1 uM f...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
University of Sussex
Curated by ChEMBL
University of Sussex
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Displacement of fluorescent tracer from ATP-binding site of N-terminal NanoLuc fused DYRK1A in HEK293 cells incubated for 2 hrs in presence of 2 uM f...More data for this Ligand-Target Pair