BDBM50637960 CHEMBL5566758

SMILES Nc1ncnc2c1c(-c1ccc3[nH]ccc3c1)nn2CCC1CCN(S(=O)(=O)c2ccc(C(F)(F)F)cc2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50637960   

TargetTGF-beta receptor type-1(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50637960(CHEMBL5566758)
Affinity DataIC50: 271nMAssay Description:Inhibition of ALK5 (unknown origin) incubated for 2 hrs in presence of ATP by ADP-Glo reagent based luminescence plate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Mouse)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50637960(CHEMBL5566758)
Affinity DataEC50:  303nMAssay Description:Inhibition of ALK5 signaling in mouse NIH3T3 cells transfected with (CAGA)12-luciferase reporter incubated for 18 hrs in presence of TGF-beta1 by dua...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed