BDBM50638242 CHEMBL5542124

SMILES C[C@H](c1ccc(F)c(F)c1)n1cnc2sc3c(c2c1=O)CCNC3

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50638242   

TargetSigma non-opioid intracellular receptor 1(Human)
Welab Barcelona

Curated by ChEMBL
LigandPNGBDBM50638242(CHEMBL5542124)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]-(+)-pentazocine from human sigma 1 receptor transfected in HEK239 cell membrane assessed as inhibition constant incubated for 12...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Welab Barcelona

Curated by ChEMBL
LigandPNGBDBM50638242(CHEMBL5542124)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of norepinephrine transporter (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistamine H1 receptor(Human)
Welab Barcelona

Curated by ChEMBL
LigandPNGBDBM50638242(CHEMBL5542124)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of histamine H1 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDelta-type opioid receptor(Human)
Welab Barcelona

Curated by ChEMBL
LigandPNGBDBM50638242(CHEMBL5542124)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of delta opioid receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
Welab Barcelona

Curated by ChEMBL
LigandPNGBDBM50638242(CHEMBL5542124)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]di-o-tolylguanidine from human sigma 2 receptor transfected in HEK239 cell membrane assessed as inhibition constant incubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Welab Barcelona

Curated by ChEMBL
LigandPNGBDBM50638242(CHEMBL5542124)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of alpha 1A adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Welab Barcelona

Curated by ChEMBL
LigandPNGBDBM50638242(CHEMBL5542124)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Welab Barcelona

Curated by ChEMBL
LigandPNGBDBM50638242(CHEMBL5542124)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 5-HT2B receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Welab Barcelona

Curated by ChEMBL
LigandPNGBDBM50638242(CHEMBL5542124)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Welab Barcelona

Curated by ChEMBL
LigandPNGBDBM50638242(CHEMBL5542124)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Human)
Welab Barcelona

Curated by ChEMBL
LigandPNGBDBM50638242(CHEMBL5542124)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of dopamine transporter (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Welab Barcelona

Curated by ChEMBL
LigandPNGBDBM50638242(CHEMBL5542124)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of alpha 2A adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed