BDBM50638252 CHEMBL5555119

SMILES O=P(O)(O)C(F)(F)c1ccc2sccc2c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50638252   

TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638252(CHEMBL5555119)
Affinity DataIC50: 2.27E+4nMAssay Description:Inhibition of SHP-1 (245 to 543 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638252(CHEMBL5555119)
Affinity DataIC50: 3.75E+4nMAssay Description:Inhibition of LYP (1 to 294 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638252(CHEMBL5555119)
Affinity DataIC50: 4.29E+4nMAssay Description:Inhibition of CD45 (620 to 1236 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638252(CHEMBL5555119)
Affinity DataIC50: 7.18E+4nMAssay Description:Inhibition of SHP-2 (224 to 528 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638252(CHEMBL5555119)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of human CDC14A using DiFMUP as substrate incubated for 10 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLaforin(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638252(CHEMBL5555119)
Affinity DataIC50: 1.22E+5nMAssay Description:Inhibition of laforin (1 to 331 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDual specificity protein phosphatase 10(Mus musculus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638252(CHEMBL5555119)
Affinity DataIC50: 2.15E+5nMAssay Description:Inhibition of mouse MKP-5 (320 to 647 residues) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins by fluorescen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638252(CHEMBL5555119)
Affinity DataIC50: 3.35E+5nMAssay Description:Inhibition of STEP (258 to 539 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638252(CHEMBL5555119)
Affinity DataIC50: 3.97E+5nMAssay Description:Inhibition of TCPTP (1 to 387 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50638252(CHEMBL5555119)
Affinity DataIC50: 4.47E+5nMAssay Description:Inhibition of PTP1B (1 to 321 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate incubated for 10 mins by f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed