BDBM50638347 CHEMBL5560628

SMILES Cc1c([C@@H](O)CN2CCc3nc(-c4ccc(C#N)c(F)c4)ncc3C2)ccc2c1COC2=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50638347   

TargetATP-sensitive inward rectifier potassium channel 1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50638347(CHEMBL5560628)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 30 mins by thallium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-sensitive inward rectifier potassium channel 1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50638347(CHEMBL5560628)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of human ROMK expressed in T-REX-CHO cells incubated for 3 to 8 mins by whole cell manual patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed