BDBM50638465 CHEMBL5567712

SMILES C=CCn1c(=O)c2cnc(Nc3ccc(N4CCN(CC)CC4)cc3)nc2n1-c1cccc(-c2cnccn2)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50638465   

TargetWee1-like protein kinase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638465(CHEMBL5567712)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human Wee1 (215 to 647 residues) using polyornithine/tyrosine (4:1) as substrate incubated for 5 mins in presence of ATP by micro beta ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetWee1-like protein kinase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50638465(CHEMBL5567712)
Affinity DataIC50: 341nMAssay Description:Inhibition of Wee1 in human U2OS cells assessed as reduction in CDK1 phosphorylation measured for 1 hr by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed