BDBM50639357 CHEMBL5565313
SMILES CCN(CC)CCNC(=O)[C@H]1CC[C@H](NC(=O)c2cnc3nc2Nc2ccc(C)c(c2)OC/C=C\CN3)CC1
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50639357
Affinity DataIC50: 1.10nMAssay Description:Inhibition of MERTK (unknown origin) expressed in HEK293 cells by MCE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Inhibition of AXL (unknown origin) by MCE assayMore data for this Ligand-Target Pair
Affinity DataEC50: 21nMAssay Description:Inhibition of MERTK in human HCC4011 cells incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 66nMAssay Description:Inhibition of TYRO3 (unknown origin) by MCE assayMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of North Carolina
Curated by ChEMBL
University of North Carolina
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of FLT3 (unknown origin) by MCE assayMore data for this Ligand-Target Pair
Affinity DataEC50: 83nMAssay Description:Inhibition of AXL autophosphorylation in human HCC4011 cells by immunoblotting analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 103nMAssay Description:Inhibition of AXL in human HCC4011 cells incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 146nMAssay Description:Inhibition of MERTK autophosphorylation in human HCC4011 cells by immunoblotting analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 4.34E+3nMAssay Description:Inhibition of TYRO3 in human HCC4011 cells incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
