BDBM50639630 CHEMBL5564352

SMILES C=C(F)C(=O)N1CCN(c2nc(CO[C@@H]3CCCN3CCCOCCC(=O)N[C@@H](C(=O)C3N[C@H](C(=O)NCc4ccc(-c5scnc5C)cc4)C[C@H]3O)C(C)(C)C)nc3c2CCN(c2cccc4cccc(Cl)c24)C3)C[C@@H]1CC#N

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50639630   

TargetGTPase KRas(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50639630(CHEMBL5564352)
Affinity DataEC50:  2.90nMAssay Description:Inhibition of KRAS G12C mutant in human NCI-H23 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetGTPase KRas(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50639630(CHEMBL5564352)
Affinity DataEC50:  3.80nMAssay Description:Inhibition of KRAS G12C mutant in human NCI-H2030 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed